The canine coronavirus is a single stranded positive RNA virus with 6-7 polypeptides, 4 of which are glycopeptides and do not contain RNA polymerase or neuraminidase. Canine coronavirus (CCV) is a serious source of viral infections in dog breeding, economic animal farming and wildlife conservation. It can cause varying degrees of gastroenteritis in dogs and is characterised by frequent vomiting, diarrhoea, depression and anorexia. The disease can occur throughout the year, but is more prevalent in winter, with sick dogs being the main infectious agent. Once the disease has occurred, it is difficult to control the infection in the same litter and in the same room. The disease is often mixed with canine microvirus, rotavirus and other gastrointestinal diseases. Puppies have a high mortality rate.
