Why do cats fail vaccinations?

Vaccinating cats is an essential step in cat ownership. Every owner who loves their pets should vaccinate their cats on time, which is both protective and responsible for them, and can also reduce the burden of medicine due to cat illness. Why will the immunization fail? I will give you a little bit of information. Reason Analysis I. Different virus or bacterial strains If a virus or bacterial strain has mutated, then the vaccination will also fail. Variation of viruses is also a problem to be noted in vaccine preparation. For example, recently, mutated strains of microviruses have been found clinically, resulting in failure of routine microvaccination. The causes of virus mutation are complex, and may be caused by the virus itself genetically, or by the stimulation of the external environment, such as some chemical or physical factors, which cause mutation of virus genes, while the abuse of some drugs such as antibiotics may also cause changes in virus resistance, making immunization less effective. Second, the maternal antibodies obtained from the mother through the placenta and colostrum are called maternal antibodies. Due to the presence of maternal antibodies, young kittens have a strong resistance to certain diseases. When to start vaccination? This is related to the level of maternal antibodies. The time for maternal antibodies to circulate in the body is different in different individuals and for different antibodies. Each individual has a period of susceptibility that varies from a few days to a few weeks, during which the level of maternal antibodies is too high to allow the vaccine to work, yet too low to be effective against infectious diseases. During this period, even after vaccination, they can still get infectious diseases. The period of susceptibility varies from litter to litter and even between individuals in the same litter. Therefore, younger cats should consider the interference of maternal antibodies and should be vaccinated according to the vaccine instructions. Generally when the cat is twelve weeks old, the maternal antibodies in the body have dropped to a non-interfering level and the last vaccination for most infectious diseases should be given at twelve weeks of age or later in order to make the cat protective. Third, the apparatus used for immunization should also be noted at the time of vaccination. Needles and syringes should be disinfected first, as unsterilized syringes, needles and drippers will degrade the performance of the vaccine; when diluting the vaccine, unsterilized or contaminated diluent will cause the vaccine to be impure; meanwhile, distilled water should be used for the preparation of water, and the use of chlorinated tap water to dilute the vaccine will reduce the immune activity of the vaccine and cause immune failure. These factors can be avoided, as long as we usually have more eyes on it. Fourth, improper use of vaccines inoculation route is not carried out according to the requirements of the vaccine, for example, in the inoculation route some drugs are injected subcutaneously, some are injected intramuscularly or nasal drops, etc., and there must be injected according to the dose. Response 1. strengthen the nutritional supplement 2. rationalize the use of drugs 3. adjust the immunization method Note that the injection of vaccines must be very healthy before the vaccine can be injected, otherwise it is easy to immunization failure.