The main manifestations of rabies Still listening to the rabies misconceptions?

You may have heard rumors about rabies: You may also be a victim of exaggerated rabies propaganda: 1. 15 million copies of the vaccine are used annually in China, 99.8% of which do not need to be vaccinated; 2. 4, vaccinated people do not need to be injected again; 5, healthy dogs transmit the virus very rarely. Truth: Some time ago, the Southern Weekend published an article criticizing the misuse of rabies vaccine and the excessive publicity of rabies in the media. These two articles were detailed, the issues questioned did exist, and the criticisms hit the nail on the head. However, these articles were so biased in their secondary distribution that the aforementioned rumor appeared on Weibo. This rumor made people think that individuals bitten by animals don’t have to do anything at all. The real symptoms of rabies Rabies, a zoonotic disease caused by the rabies virus. This virus has a strong affinity for nerve tissue, and the virus enters the body and gradually invades the nerve center, starting with the nerves around the bite site. Clinical symptoms such as fear of water, difficulty in breathing, and difficulty in swallowing may occur. When the disease process enters the final stage, the virus may travel along the nerves to various organs throughout the body, such as the eyes, tongue, salivary glands, respiratory muscles, heart, etc. The patient may eventually die of respiratory paralysis and circulatory failure. The entire course of the disease progresses rapidly, ranging from 2 days to a week from onset to death. The incubation period of rabies varies, with most patients experiencing an incubation period of 1-3 months before the onset of the disease, but there are cases where the incubation period is less than 1 week and more than 1 year, while children, head and face bites, and deep wounds with incomplete debridement have a short incubation period. The incubation period experienced by patients before the onset of the disease varies in length, mostly 1-3 months, but also less than 1 week and more than 1 year, while children, head and face bites, and deep wounds with incomplete debridement have a short incubation period. Whether healthy dogs transmit rabies virus or not actually includes dogs, cats, bats and a variety of other carnivorous animals. Of the animals mentioned above, dogs are the main ones causing transmission. A national epidemiological survey of human rabies mentioned [5] that 91% of the 711 cases observed in areas with high rabies prevalence in China were attacked by dogs. According to the WHO animal contact classification criteria, 6.3% of these patients had only type I contact with animals (i.e., touching or keeping the animal, or being licked by the animal on intact skin), 30.4% had type II contact (i.e., minor abrasions of the skin causing minor breakage or no bleeding), and 63.3% had type III contact (penetrating skin bites or scratches, or mucosal contamination). In other words, the higher the degree of skin damage after contact with the animal, the greater the likelihood of rabies development. The earlier the rabies vaccination is given, the more effective it is. However, even if the vaccine is given more than 24 hours later, the vaccine can be effective as long as the person has not developed the disease before the vaccine takes effect. Rabies vaccine is effective in the following two ways: 1. Active immunity, which is the immunity established by the specific response of the body to an antigenic stimulus. Active immunity takes a few days, weeks or more to appear, but can be maintained for a long time or even for life and is easily reactivated by injection of the required antigen; 2. Passive immunity, which refers to the acquisition of immunity by the body through the acquisition of exogenous immune effector molecules (such as antibodies, etc.) or immune effector cells.